Summary of NID2
The gene codes for a protein, nidogen 2. It maintains the structure of collagen [R].
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The Function of NID2
Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.
Protein names
Recommended name:
Nidogen-2Short name:
NID-2Alternative name(s):
Osteonidogen- RS730532 (NID2) ??
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Top Gene-Substance Interactions
Substances That Increase NID2
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Substances That Decrease NID2
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Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Heart, placenta and bone. Less in pancreas, kidney and skeletal muscle.