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  3. NID2

NID2 (Nidogen 2)

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Summary of NID2

The gene codes for a protein, nidogen 2. It maintains the structure of collagen [R].

0 users want this gene increased, 0 users want it decreased

The Function of NID2

Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.

Protein names

Recommended name:

Nidogen-2

Short name:

NID-2

Alternative name(s):

Osteonidogen

NID2 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS730532 (NID2) ??

Top Gene-Substance Interactions

Substances That Increase NID2

Substances Interaction Organism Category

Substances That Decrease NID2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • HNF-1A
  • HNF-1
  • FOXF2
  • SREBP-1a
  • SREBP-1c
  • SREBP-1b
  • MIF-1

Tissue specificity:

Heart, placenta and bone. Less in pancreas, kidney and skeletal muscle.

Gene Pathways:

  • Extracellular matrix organization

Molecular Function:

  • Calcium Ion Binding
  • Collagen Binding

Biological Processes:

  • Basement Membrane Organization
  • Cell Adhesion
  • Cell-Matrix Adhesion
  • Extracellular Matrix Organization
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| nid1| A306_05096| CB1_001455006| D623_10018097| entactin 2| entactin-2| H920_08872| I79_020564| Ly111| M959_02724| N300_12235| N303_03972| nid-2| nidogen 1| nidogen-2| nidogen 2 (osteonidogen)| osteonidogen| PAL_GLEAN10023304| PANDA_016197| TREES_T100013455| Y1Q_025622| Y956_12461| nid2

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