The Function of NFYC
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
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Protein names
Recommended name:
Nuclear transcription factor Y subunit gammaShort name:
NF-YCAlternative name(s):
CAAT box DNA-binding protein subunit CNuclear transcription factor Y subunit C
Transactivator HSM-1/2
- RS10489167 (NFYC) ??
- RS4660456 (NFYC) ??
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Top Gene-Substance Interactions
Substances That Increase NFYC
| Substances | Interaction | Organism | Category |
Substances That Decrease NFYC
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Molecular Function:
- Dna Binding
- Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Dna Binding
- Transcriptional Activator Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding
- Transcription Coactivator Activity
- Transcription Factor Activity, Sequence-Specific Dna Binding
Biological Processes:
- Protein Folding
- Regulation Of Transcription, Dna-Templated
- Regulation Of Transcription From Rna Polymerase Ii Promoter