Summary of NEFM
The gene codes for a protein, neurofilament, medium polypeptide. It is used as a biomarker of damage in neurons [R].
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The Function of NEFM
Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
Protein names
Recommended name:
Neurofilament medium polypeptideShort name:
NF-MAlternative name(s):
160 kDa neurofilament proteinNeurofilament 3
Neurofilament triplet M protein
- RS1457266 (NEFM) ??
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Top Gene-Substance Interactions
NEFM Interacts with These Diseases
| Disease | Score |
Substances That Increase NEFM
| Substances | Interaction | Organism | Category |
Substances That Decrease NEFM
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Neurofilament Bundle Assembly
- Axon Development
- Mitophagy In Response To Mitochondrial Depolarization