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  3. NDUFB8

NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8)

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The Function of NDUFB8

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

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Protein names

Recommended name:

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

Short name:

CI-ASHI

Alternative name(s):

Complex I-ASHI
NADH-ubiquinone oxidoreductase ASHI subunit

Top Gene-Substance Interactions

NDUFB8 Interacts with These Diseases

Disease Score

Substances That Increase NDUFB8

Substances Interaction Organism Category

Substances That Decrease NDUFB8

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • ER-alpha
  • Evi-1
  • CUTL1
  • Pax-6
  • PPAR-alpha
  • TGIF
  • p300

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Alzheimer's disease
  • Huntington's disease
  • Oxidative phosphorylation
  • Parkinson's disease

Molecular Function:

  • Nadh Dehydrogenase (Ubiquinone) Activity

Biological Processes:

  • Mitochondrial Electron Transport, Nadh To Ubiquinone
  • Mitochondrial Respiratory Chain Complex I Assembly
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_12452| AS27_02558| AS28_05923| ASHI| CI-ASHI| complex I-ASHI| complex I ASHI subunit| D623_10025655| GW7_15871| I79_016388| M959_03580| MDA_GLEAN10023394| mitochondrial complex I subunit NDUFB8| mitochondrial NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8| mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8| N300_11771| N301_10692| N302_13442| N303_09236| N305_07128| N306_08213| N307_06096| N308_00288| N309_00810| N310_05202| N311_10083| N312_09649| N320_10199| N321_00425| N322_10268| N324_10970| N325_10558| N326_11088| N327_06901| N328_00240| N329_08405| N330_11175| N331_09201| N332_05453| N333_00052| N334_02145| N335_06752| N336_10426| N339_03897| N341_00159| NADH dehydrogenase 1 beta subcomplex 8| NADH dehydrogenase 1 beta subcomplex 8-like| NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial| NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8| NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8| NADH dehydrogenase ubiquinone 1 beta subcomplex 8| NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Uncharacterized protein| NADH-ubiquinone oxidoreductase ASHI subunit| NADH:ubiquinone oxidoreductase ASHI subunit| NDUB8| nduf8| OXPHOS complex I ASHI subunit| PAL_GLEAN10018269| PANDA_013631| putative NADH dehydrogenase 1 beta subcomplex 8| TREES_T100012244| UY3_00940| Y1Q_010609| Y956_01565| Z169_12766| ndufb8

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