The Function of NDUFB8
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
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Protein names
Recommended name:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrialShort name:
CI-ASHIAlternative name(s):
Complex I-ASHINADH-ubiquinone oxidoreductase ASHI subunit
Top Gene-Substance Interactions
NDUFB8 Interacts with These Diseases
| Disease | Score |
Substances That Increase NDUFB8
| Substances | Interaction | Organism | Category |
Substances That Decrease NDUFB8
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Mitochondrial Electron Transport, Nadh To Ubiquinone
- Mitochondrial Respiratory Chain Complex I Assembly