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  3. MTSS1

MTSS1 (MTSS1, I-BAR domain containing)

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The Function of MTSS1

May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.

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Protein names

Recommended name:

Metastasis suppressor protein 1

Alternative name(s):

Metastasis suppressor YGL-1
Missing in metastasis protein

MTSS1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS11781525 (MTSS1) ??
  2. RS2116081 (MTSS1) ??

Top Gene-Substance Interactions

MTSS1 Interacts with These Diseases

Disease Score

Substances That Increase MTSS1

Substances Interaction Organism Category

Substances That Decrease MTSS1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • PPAR-gamma2
  • RORalpha1
  • p53
  • RORalpha2
  • AP-2gamma
  • Sox9

Tissue specificity:

Expressed in many tissues, including spleen, thymus, prostate, testis, uterus, colon, and peripheral blood.

Molecular Function:

  • Actin Monomer Binding
  • Receptor Binding
  • Identical Protein Binding

Biological Processes:

  • Actin Cytoskeleton Organization
  • Cell Adhesion
  • Cellular Response To Fluid Shear Stress
  • Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis
  • Glomerulus Morphogenesis
  • Microspike Assembly
  • Movement Of Cell Or Subcellular Component
  • Negative Regulation Of Epithelial Cell Proliferation
  • Nephron Tubule Epithelial Cell Differentiation
  • Plasma Membrane Organization
  • Renal Tubule Morphogenesis
  • Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
  • Positive Regulation Of Defense Response To Virus By Host
  • Xenophagy
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| actin monomer-binding protein| AS27_11184| AS28_00492| CB1_000444018| D623_10018153| H920_18188| homeobox protein 5| I79_025117| M959_00133| MDA_GLEAN10010559| metastasis suppressor 1| Metastasis suppressor protein 1| metastasis suppressor YGL-1| MIM| MIMA| MIMB| missing in metastasis protein| MTSS1-like protein-like| N300_08466| N301_04730| N302_07462| N303_07789| N305_13269| N306_03207| N307_11176| N308_00853| N309_10843| N310_03636| N311_06384| N312_13148| N320_00896| N321_12483| N322_02514| N324_04916| N325_08028| N326_04578| N327_02672| N328_06247| N329_01504| N332_06604| N333_10480| N334_10889| N336_11835| N339_00968| N340_05870| N341_01821| PAL_GLEAN10021374| PANDA_019348| TREES_T100005276| UY3_12614| Y1Q_024739| Y956_13124| Z169_11813| mtss1

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