Summary of MTCH2
The gene codes a protein, mitochondrial carrier 2. It plays a key role in metabolic pathways and cell functions. Polymorphisms are linked to obesity [R].
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The Function of MTCH2
The substrate transported is not yet known. Induces mitochondrial depolarization.
Protein names
Recommended name:
Mitochondrial carrier homolog 2Alternative name(s):
Met-induced mitochondrial protein- RS10838738 (MTCH2) ??
- RS3817334 (MTCH2) ??
- RS4752856 (MTCH2) ??
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Top Gene-Substance Interactions
MTCH2 Interacts with These Diseases
| Disease | Score |
Substances That Increase MTCH2
| Substances | Interaction | Organism | Category |
Substances That Decrease MTCH2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Biological Processes:
- Positive Regulation Of Apoptotic Process
- Protein Localization To Mitochondrion
- Hepatocyte Apoptotic Process
- Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process