The Function of MLANA
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
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Protein names
Recommended name:
Melanoma antigen recognized by T-cells 1Short name:
MART-1Alternative name(s):
Antigen LB39-AAAntigen SK29-AA
Protein Melan-A
- RS2150702 (MLANA) ??
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Top Gene-Substance Interactions
Substances That Increase MLANA
| Substances | Interaction | Organism | Category |
Substances That Decrease MLANA
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expression is restricted to melanoma and melanocyte cell lines and retina.
*synonyms