The Function of MEPE
Promotes renal phosphate excretion and modulates mineralization.
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Protein names
Recommended name:
Matrix extracellular phosphoglycoproteinShort name:
OF45Alternative name(s):
Osteoblast/osteocyte factor 45- RS12644436 (MEPE) ??
- RS1463104 (MEPE) ??
- RS1471403 (MEPE) ??
- RS6532023 (MEPE) ??
- RS7698623 (MEPE) ??
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Top Gene-Substance Interactions
Substances That Increase MEPE
Substances | Interaction | Organism | Category |
Substances That Decrease MEPE
Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed by osteoblasts. Secreted from oncogenic hypophosphataemic tumors.
Molecular Function:
Biological Processes:
- Biomineral Tissue Development
- Negative Regulation Of Bone Mineralization
- Regulation Of Bone Remodeling
- Skeletal System Development