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  3. MEPE

MEPE (Matrix extracellular phosphoglycoprotein)

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The Function of MEPE

Promotes renal phosphate excretion and modulates mineralization.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Matrix extracellular phosphoglycoprotein

Short name:

OF45

Alternative name(s):

Osteoblast/osteocyte factor 45

MEPE SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS12644436 (MEPE) ??
  2. RS1463104 (MEPE) ??
  3. RS1471403 (MEPE) ??
  4. RS6532023 (MEPE) ??
  5. RS7698623 (MEPE) ??

Top Gene-Substance Interactions

Substances That Increase MEPE

Substances Interaction Organism Category

Substances That Decrease MEPE

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • AP-1
  • c-Jun
  • c-Fos
  • Fra-1
  • JunD

Tissue specificity:

Expressed by osteoblasts. Secreted from oncogenic hypophosphataemic tumors.

Molecular Function:

  • Extracellular Matrix Protein Binding
  • Extracellular Matrix Structural Constituent

Biological Processes:

  • Biomineral Tissue Development
  • Negative Regulation Of Bone Mineralization
  • Regulation Of Bone Remodeling
  • Skeletal System Development
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| AS27_05724| AS28_03138| CB1_000209004| D623_10021161| H920_16095| I79_024801| matrix extracellular phosphoglycoprotein with ASARM motif (bone)| matrix, extracellular phosphoglycoprotein with ASARM motif (bone)| matrix, extracellular phosphoglycoprotein with ASARM motif (bone)-like protein| MDA_GLEAN10007998| N302_06061| N305_05234| N306_01168| N311_06974| N312_07391| N322_06246| N324_02934| N325_11981| N326_01841| N327_04046| N330_14312| N332_02409| N334_08802| N335_06593| OC-116| Of45| osteoblast/osteocyte factor 45| osteoregulin| ovocleidin-116| ovocleidin-116 protein| PAL_GLEAN10010906| PANDA_001446| TREES_T100011615| Y956_11705| mepe

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