Protein names
Recommended name:
NADP-dependent malic enzymeShort name:
NADP-MEAlternative name(s):
Malic enzyme 1- RS12195417 (ME1) ??
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Top Gene-Substance Interactions
ME1 Interacts with These Diseases
| Disease | Score |
Substances That Increase ME1
| Substances | Interaction | Organism | Category |
Substances That Decrease ME1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed in all tissues tested including liver, placenta and white adipose tissue.
Gene Pathways:
Cofactor:
Divalent metal cations. Prefers magnesium or manganese.
Molecular Function:
- Malic Enzyme Activity
- Malate Dehydrogenase (Decarboxylating) (Nad+) Activity
- Malate Dehydrogenase (Decarboxylating) (Nadp+) Activity
- Oxaloacetate Decarboxylase Activity
- Electron Carrier Activity
- Manganese Ion Binding
- Adp Binding
- Nadp Binding
- Nad Binding
Biological Processes:
- Carbohydrate Metabolic Process
- Malate Metabolic Process
- Nadp Biosynthetic Process
- Response To Hormone
- Response To Carbohydrate
- Protein Tetramerization
- Regulation Of Nadp Metabolic Process