Summary of MAOB
MAOB (monoamine oxidase B) encodes a protein that plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system (R).
It is associated with higher risk for Parkinson's and Alzheimer diseases (R, R).
It's better to have this gene decreased
most of the time.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Amine oxidase [flavin-containing] BShort name:
MAO-BAlternative name(s):
Monoamine oxidase type B- RS1799836 (MAOB) ??
- RS3027409 (MAOB) ??
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Top Gene-Substance Interactions
MAOB Interacts with These Diseases
| Disease | Score |
Substances That Increase MAOB
| Substances | Interaction | Organism | Category |
Substances That Decrease MAOB
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Dopamine Catabolic Process
- Hydrogen Peroxide Biosynthetic Process
- Negative Regulation Of Serotonin Secretion
- Neurotransmitter Catabolic Process
- Positive Regulation Of Dopamine Metabolic Process
- Response To Aluminum Ion
- Response To Corticosterone
- Response To Ethanol
- Response To Lipopolysaccharide
- Response To Selenium Ion
- Response To Toxic Substance
- Substantia Nigra Development
Drug Bank:
- Ephedra
- Flavin Adenine Dinucleotide
- Amantadine
- Dopamine
- Furazolidone
- Isocarboxazid
- Linezolid
- Methamphetamine
- Moclobemide
- Pargyline
- Phenelzine
- Phentermine
- Procaine
- Selegiline
- Sertraline
- Tranylcypromine
- Zonisamide
- Nicotine
- Amphetamine
- Nandrolone Decanoate
- Rasagiline