The Function of LTB
Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.
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Protein names
Recommended name:
Lymphotoxin-betaShort name:
TNF-CAlternative name(s):
LT-betaTumor necrosis factor C
Tumor necrosis factor ligand superfamily member 3
Top Gene-Substance Interactions
Substances That Increase LTB
| Substances | Interaction | Organism | Category |
Substances That Decrease LTB
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Spleen and thymus.
Gene Pathways:
Molecular Function:
Biological Processes:
- Immune Response
- Signal Transduction
- Cell-Cell Signaling
- Gene Expression
- Tumor Necrosis Factor-Mediated Signaling Pathway
- Skin Development
- Positive Regulation Of Interleukin-12 Biosynthetic Process
- Lymph Node Development