The Function of LMO2
Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
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Protein names
Recommended name:
Rhombotin-2Short name:
LMO-2Alternative name(s):
Cysteine-rich protein TTG-2LIM domain only protein 2
T-cell translocation protein 2
- RS11032423 (LMO2) ??
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Top Gene-Substance Interactions
Substances That Increase LMO2
| Substances | Interaction | Organism | Category |
Substances That Decrease LMO2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Molecular Function:
- Rna Polymerase Ii Regulatory Region Sequence-Specific Dna Binding
- Rna Polymerase Ii Transcription Factor Activity, Sequence-Specific Dna Binding
- Rna Polymerase Ii Activating Transcription Factor Binding
- Transcriptional Activator Activity, Rna Polymerase Ii Transcription Factor Binding
- Transcriptional Activator Activity, Rna Polymerase Ii Transcription Regulatory Region Sequence-Specific Binding
- Zinc Ion Binding
- Bhlh Transcription Factor Binding
- Cofactor Binding
- E-Box Binding
Biological Processes:
- Multicellular Organism Development
- Mrna Transcription From Rna Polymerase Ii Promoter
- Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
- Cellular Response To Thyroid Hormone Stimulus