The Function of LIPT1
Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
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Protein names
Recommended name:
Lipoyltransferase 1, mitochondrialAlternative name(s):
Lipoate biosynthesis proteinLipoate-protein ligase
Lipoyl ligase
Top Gene-Substance Interactions
Substances That Increase LIPT1
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Substances That Decrease LIPT1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Highly expressed in skeletal muscle and heart, moderately in kidney and pancreas, and detected at lower levels in liver, brain, placenta and lung.
Molecular Function:
- Lipoate-Protein Ligase Activity
- Lipoyltransferase Activity
- Transferase Activity, Transferring Acyl Groups
Biological Processes:
- Cellular Protein Modification Process
- Glyoxylate Metabolic Process
- Lipid Metabolic Process
- Protein Lipoylation