The Function of LIMK2
Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.
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Protein names
Recommended name:
LIM domain kinase 2Short name:
LIMK-2- RS2106294 (LIMK2) ??
- RS2413045 (LIMK2) ??
- RS4141404 (LIMK2) ??
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Top Gene-Substance Interactions
Substances That Increase LIMK2
| Substances | Interaction | Organism | Category |
Substances That Decrease LIMK2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed.