Summary of LGALS2
LGALS2 encodes a protein that acts as a clumping molecule (lectin) for a class of sugars called beta galactosides (R). Genetic variation of a single nucleotide on one section of noncoding DNA can greatly affect the degree of the protein expression, which is related to increased risk of heart attack (R).
The Function of LGALS2
This protein binds beta-galactoside. Its physiological function is not yet known.
Protein names
Recommended name:
Galectin-2Short name:
HL14Alternative name(s):
Gal-2Beta-galactoside-binding lectin L-14-II
Lactose-binding lectin 2
S-Lac lectin 2
- RS12157904 (LGALS2) ??
- RS7291467 (LGALS2) ??
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Top Gene-Substance Interactions
LGALS2 Interacts with These Diseases
| Disease | Score |
Substances That Increase LGALS2
| Substances | Interaction | Organism | Category |
Substances That Decrease LGALS2
| Substances | Interaction | Organism | Category |
Advanced Summary
From NCBI Gene: Myocardial infarction 1
From NCBI Gene: The protein encoded by this gene is a soluble beta-galactoside binding lectin . The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction. [provided by RefSeq, Jul 2008] From UniProt: This protein binds beta-galactoside. Its physiological function is not yet known.
Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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