The Function of KMT2D
Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.
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Protein names
Recommended name:
Histone-lysine N-methyltransferase 2DAlternative name(s):
Lysine N-methyltransferase 2DALL1-related protein
Myeloid/lymphoid or mixed-lineage leukemia protein 2
- RS10875912 (KMT2D) ??
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Top Gene-Substance Interactions
KMT2D Interacts with These Diseases
| Disease | Score |
Substances That Increase KMT2D
| Substances | Interaction | Organism | Category |
Substances That Decrease KMT2D
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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