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  3. IVNS1ABP

IVNS1ABP (Influenza virus NS1A binding protein)

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The Function of IVNS1ABP

Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

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Protein names

Recommended name:

Influenza virus NS1A-binding protein

Short name:

NS1-BP

Alternative name(s):

NS1-binding protein
Aryl hydrocarbon receptor-associated protein 3

Top Gene-Substance Interactions

IVNS1ABP Interacts with These Diseases

Disease Score

Substances That Increase IVNS1ABP

Substances Interaction Organism Category

Substances That Decrease IVNS1ABP

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • AhR
  • c-Myc

Biological Processes:

  • Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
  • Response To Virus
  • Rna Splicing
  • Transcription From Rna Polymerase Iii Promoter
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_05743| aryl hydrocarbon receptor-associated 3| aryl hydrocarbon receptor-associated protein 3| AS27_08106| AS28_01882| CB1_000818019| EGK_01851| EH28_16132| FLARA3| GW7_09814| HSPC068| Influenza virus NS1A-binding protein| influenza virus NS1A-binding protein homolog| Influenza virus NS1A-binding protein homolog A| influenza virus NS1A binding protein isoform a isoform 2-like protein| Influenza virus NS1A-binding protein like protein| Influenza virus NS1A-binding protein-like protein| kelch family protein Nd1| kelch family protein Nd1-L| kelch-like family member 39| KLHL39| M959_12546| MDA_GLEAN10017482| N300_02688| N301_05338| N302_03582| N303_14879| N306_02902| N307_12455| N309_11519| N311_10401| N312_12038| N320_11849| N321_12970| N322_12875| N324_05595| N325_06638| N326_12170| N327_02000| N328_02953| N329_08782| N330_07606| N331_09948| N332_00647| N333_09866| N334_13333| N335_11763| N336_11444| N339_05422| N340_03749| N341_06758| NCX downstream gene 1| ND1| Nd1-L| ND1-L2| Nd1-S| NS-1| ns1ba| NS1-binding protein| NS1-binding protein homolog| NS1BP| NS1-BP| PAL_GLEAN10017655| PANDA_009709| putative influenza virus NS1A-binding protein| TREES_T100002679| Y1Q_018684| Y956_06396| Z169_07300| ivns1abp

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