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  3. ITGB5

ITGB5 (Integrin subunit beta 5)

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The Function of ITGB5

(Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C.

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Protein names

Recommended name:

Integrin beta-5

Top Gene-Substance Interactions

ITGB5 Interacts with These Diseases

Disease Score

Substances That Increase ITGB5

Substances Interaction Organism Category

Substances That Decrease ITGB5

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • RORalpha1
  • Nkx5-1
  • HSF2

Gene Pathways:

  • Immune System
  • Regulation of actin cytoskeleton
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
  • Extracellular matrix organization
  • Dilated cardiomyopathy
  • Hypertrophic cardiomyopathy (HCM)
  • Phagosome
  • Muscle contraction

Molecular Function:

  • Virus Receptor Activity

Biological Processes:

  • Antigen Processing And Presentation Of Exogenous Peptide Antigen Via Mhc Class I, Tap-Dependent
  • Cell-Matrix Adhesion
  • Endodermal Cell Differentiation
  • Epithelial Cell-Cell Adhesion
  • Extracellular Matrix Organization
  • Integrin-Mediated Signaling Pathway
  • Muscle Contraction
  • Stress Fiber Assembly
  • Transforming Growth Factor Beta Receptor Signaling Pathway
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| beta5| beta-5| A306_03906| AS27_06811| AS28_05505| [b]5| [b]-5| [b]5A| [b]5B| CB1_001278002| D623_10032669| ESTM23| I79_000655| integrin beta 5| integrin, beta 5| Integrin beta-5| M91_04240| M959_07013| N300_03638| N301_09544| N302_02337| N303_07893| N305_07469| N306_00795| N307_11360| N308_08243| N309_09297| N310_10546| N320_12019| N321_14022| N322_13448| N325_07935| N326_07993| N327_02468| N329_05357| N330_14218| N332_12188| N333_01294| N336_10965| N339_13048| N340_00323| PAL_GLEAN10006562| PANDA_004928| RGD1563276| testis secretory sperm-binding protein Li 217p| TREES_T100009175| Y1Q_031735| Y956_05766| Z169_07862| itgb5

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