• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. IRS2

IRS2 (Insulin receptor substrate 2)

Loading...

The Function of IRS2

May mediate the control of various cellular processes by insulin.

0 users want this gene increased, 0 users want it decreased

Top Gene-Substance Interactions

IRS2 Interacts with These Diseases

Disease Score

Substances That Increase IRS2

Substances Interaction Organism Category

Substances That Decrease IRS2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • AP-1
  • NF-kappaB1
  • FOXO1a
  • FOXO1
  • SREBP-1a
  • SREBP-1c
  • SREBP-1b

Gene Pathways:

  • Disease
  • Immune System
  • Signal Transduction
  • Adipocytokine signaling pathway
  • Mus musculus biological processes
  • Neurotrophin signaling pathway
  • Insulin signaling pathway
  • Aldosterone-regulated sodium reabsorption
  • Type II diabetes mellitus

Molecular Function:

  • 1-Phosphatidylinositol-3-Kinase Activity
  • Insulin Receptor Binding
  • Phosphatidylinositol 3-Kinase Binding
  • Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Activity
  • Ras Guanyl-Nucleotide Exchange Factor Activity
  • Signal Transducer Activity

Biological Processes:

  • Brain Development
  • Cell Proliferation
  • Cellular Response To Glucose Stimulus
  • Cellular Response To Insulin Stimulus
  • Glucose Metabolic Process
  • Insulin Receptor Signaling Pathway
  • Lipid Homeostasis
  • Mammary Gland Development
  • Mapk Cascade
  • Negative Regulation Of B Cell Apoptotic Process
  • Negative Regulation Of Kinase Activity
  • Negative Regulation Of Plasma Membrane Long-Chain Fatty Acid Transport
  • Phosphatidylinositol-Mediated Signaling
  • Positive Regulation Of B Cell Proliferation
  • Positive Regulation Of Cell Migration
  • Positive Regulation Of Cell Proliferation
  • Positive Regulation Of Fatty Acid Beta-Oxidation
  • Positive Regulation Of Glucose Import
  • Positive Regulation Of Glucose Metabolic Process
  • Positive Regulation Of Glycogen Biosynthetic Process
  • Positive Regulation Of Insulin Secretion
  • Positive Regulation Of Mesenchymal Cell Proliferation
  • Regulation Of Lipid Metabolic Process
  • Regulation Of Phosphatidylinositol 3-Kinase Signaling
  • Response To Glucose
  • Signal Transduction
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| IRS-1| irs1| 4PS| AS28_10469| D623_10030994| H920_03573| I79_024331| insulin receptor substrate 1| Insulin receptor substrate 2-B| IRS-2| irsu| MDA_GLEAN10017054| N300_06744| N302_15320| N303_09338| N307_07210| N308_11650| N322_10592| N336_10094| PAL_GLEAN10013724| PANDA_019647| tyrosine kinase substrate| Y956_11957| irs2

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved