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  3. INHBC

INHBC (Inhibin beta C subunit)

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The Function of INHBC

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

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Protein names

Recommended name:

Inhibin beta C chain

Alternative name(s):

Activin beta-C chain

INHBC SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS3741414 (INHBC) ??
  2. RS61352607 (INHBC) ??

Top Gene-Substance Interactions

Substances That Increase INHBC

Substances Interaction Organism Category

Substances That Decrease INHBC

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • GR
  • GR-alpha
  • p53
  • STAT5A
  • c-Myb

Tissue specificity:

Expressed in benign prostatic hyperplasia.

Gene Pathways:

  • Cytokine-cytokine receptor interaction
  • TGF-beta signaling pathway

Molecular Function:

  • Cytokine Activity
  • Transforming Growth Factor Beta Receptor Binding

Biological Processes:

  • Cell Development
  • Positive Regulation Of Pathway-Restricted Smad Protein Phosphorylation
  • Regulation Of Apoptotic Process
  • Regulation Of Mapk Cascade
  • Smad Protein Signal Transduction
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

activin beta-C chain| activin/inhibin beta C| CB1_000607004| EGK_03834| H920_14026| IHBC| inhibin beta-C| inhibin, beta C| inhibin beta C chain| inhibin beta C chain-like protein| MDA_GLEAN10006659| N302_04743| N333_05746| N340_07332| PAL_GLEAN10004858| PANDA_004118| TREES_T100018340| UY3_00353| inhbc

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