The Function of INHBC
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Inhibin beta C chainAlternative name(s):
Activin beta-C chain- RS3741414 (INHBC) ??
- RS61352607 (INHBC) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
Substances That Increase INHBC
| Substances | Interaction | Organism | Category |
Substances That Decrease INHBC
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed in benign prostatic hyperplasia.
Gene Pathways:
Molecular Function:
Biological Processes:
- Cell Development
- Positive Regulation Of Pathway-Restricted Smad Protein Phosphorylation
- Regulation Of Apoptotic Process
- Regulation Of Mapk Cascade
- Smad Protein Signal Transduction