Summary of IL5
The Function of IL5
Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
Protein names
Recommended name:
Interleukin-5Short name:
TRFAlternative name(s):
IL-5B-cell differentiation factor I
Eosinophil differentiation factor
T-cell replacing factor
- RS2069812 (IL5) ??
- RS4143832 (IL5) ??
- RS4705952 (IL5) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
IL5 Interacts with These Diseases
| Disease | Score |
Substances That Increase IL5
| Substances | Interaction | Organism | Category |
Substances That Decrease IL5
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
- Cytokine Activity
- Interleukin-5 Receptor Binding
- Protein Tyrosine Kinase Activity
- Ras Guanyl-Nucleotide Exchange Factor Activity
Biological Processes:
- Cytokine-Mediated Signaling Pathway
- Immune Response
- Inflammatory Response
- Mapk Cascade
- Positive Regulation Of B Cell Proliferation
- Positive Regulation Of Eosinophil Differentiation
- Positive Regulation Of Immunoglobulin Secretion
- Positive Regulation Of Jak-Stat Cascade
- Positive Regulation Of Peptidyl-Tyrosine Phosphorylation
- Positive Regulation Of Podosome Assembly
- Positive Regulation Of Sequence-Specific Dna Binding Transcription Factor Activity
- Positive Regulation Of Transcription, Dna-Templated
Drug Bank:
- Mepolizumab
- Pranlukast