Summary of IL24
The gene codes for a protein, interleukin 24. It is induced during terminal differentiation in melanoma cells [R].
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The Function of IL24
Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation.
Protein names
Recommended name:
Interleukin-24Short name:
IL-24Alternative name(s):
Melanoma differentiation-associated gene 7 proteinMDA-7
Suppression of tumorigenicity 16 protein
- RS1150258 (IL24) ??
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Top Gene-Substance Interactions
IL24 Interacts with These Diseases
| Disease | Score |
Substances That Increase IL24
| Substances | Interaction | Organism | Category |
Substances That Decrease IL24
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Up-regulated in melanoma cells induced to terminally differentiate.
Gene Pathways:
Molecular Function:
Biological Processes:
- Apoptotic Process
- Inflammatory Response
- Immune Response
- Positive Regulation Of Cell Proliferation
- Negative Regulation Of Cell Proliferation
- Negative Regulation Of Cell Migration
- Serine Phosphorylation Of Stat3 Protein
- Wound Healing
- Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein
- Positive Regulation Of Jak-Stat Cascade
- Cellular Response To Lipopolysaccharide
- Cellular Response To Interleukin-4