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  3. IBSP

IBSP (Integrin binding sialoprotein)

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Summary of IBSP

The gene codes for a protein, integrin binding sialoprotein. It is an important structural protein of the bone matrix [R].

0 users want this gene increased, 0 users want it decreased

The Function of IBSP

Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.

Protein names

Recommended name:

Bone sialoprotein 2

Short name:

BSP II

Alternative name(s):

Bone sialoprotein II
Cell-binding sialoprotein
Integrin-binding sialoprotein

IBSP SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS1054627 (IBSP) ??

Top Gene-Substance Interactions

IBSP Interacts with These Diseases

Disease Score

Substances That Increase IBSP

Substances Interaction Organism Category

Substances That Decrease IBSP

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • CBF-B
  • NF-YB
  • NF-kappaB1
  • NF-YC
  • CBF-C

Gene Pathways:

  • Extracellular matrix organization

Biological Processes:

  • Bone Mineralization
  • Cell Adhesion
  • Cellular Response To Growth Factor Stimulus
  • Extracellular Matrix Organization
  • Osteoblast Differentiation
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| BSP| A306_06578| AS27_05723| AS28_03137| bnsp| bone sialoprotein| Bone sialoprotein 2| bone sialoprotein 2-like protein| bone sialoprotein II| Bsp2| bsp-ii| BSPII| BSP II| CB1_000209005| cell-binding sialoprotein| D623_10021162| GW7_20318| H920_16094| integrin-binding sialoprotein| integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II)| M959_04883| MDA_GLEAN10007999| N300_03088| N302_06060| N303_09477| N305_05233| N306_01167| N309_00769| N312_07392| N320_02463| N321_06967| N322_06247| N327_04047| N329_03783| N330_14313| N333_02655| N335_06594| N336_09870| N340_06824| PAL_GLEAN10010905| PANDA_001447| sp-ii| TREES_T100011614| Y1Q_014187| Y956_11706| Z169_13677| ibsp

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