The Function of HSD17B3
Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH.
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Protein names
Recommended name:
Testosterone 17-beta-dehydrogenase 3Alternative name(s):
17-beta-hydroxysteroid dehydrogenase type 317-beta-HSD 3
Short chain dehydrogenase/reductase family 12C member 2
Testicular 17-beta-hydroxysteroid dehydrogenase
- RS7042315 (HSD17B3) ??
- RS8190560 (HSD17B3) ??
- RS8190569 (HSD17B3) ??
- RS9785234 (HSD17B3) ??
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Top Gene-Substance Interactions
HSD17B3 Interacts with These Diseases
| Disease | Score |
Substances That Increase HSD17B3
| Substances | Interaction | Organism | Category |
Substances That Decrease HSD17B3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Testis.