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  3. HOXA10

HOXA10 (Homeobox A10)

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The Function of HOXA10

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'.

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Protein names

Recommended name:

Homeobox protein Hox-A10

Short name:

PL

Alternative name(s):

Homeobox protein Hox-1.8
Homeobox protein Hox-1H

Top Gene-Substance Interactions

HOXA10 Interacts with These Diseases

Disease Score

Substances That Increase HOXA10

Substances Interaction Organism Category

Substances That Decrease HOXA10

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • ER-alpha
  • p53
  • Sp1
  • Meis-1
  • Gfi-1
  • Meis-1b
  • Msx-1

Molecular Function:

  • Histone Deacetylase Binding
  • Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Dna Binding
  • Transcriptional Activator Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding

Biological Processes:

  • Anterior/Posterior Pattern Specification
  • Embryonic Limb Morphogenesis
  • Male Gonad Development
  • Multicellular Organism Development
  • Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Proximal/Distal Pattern Formation
  • Single Fertilization
  • Skeletal System Development
  • Spermatogenesis
  • Uterus Development
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| PL| AS27_03392| AS28_05440| D623_10034029| EH28_23856| homeo box A10| homeobox A10 isoform a (predicted), 3 prime| homeobox A10 isoform a (predicted), 5 prime| homeobox protein 1H| homeobox protein A10| homeobox protein Hox-1.8| homeobox protein Hox-1H| homeobox protein HOXA10| Homeobox protein Hox-A10| homeobox protein HoxA10a| Homeobox protein Hox-A10a| homeobox protein Hox-B6 pseudogene| HOX1| Hox-1.8| HOX1.8| HOX1H| Hoxa-10| Hox A10| HoxA10a| Hox-A10a| I79_008458| M91_04224| M959_00238| N300_01074| N301_09163| N303_02263| N305_02620| N306_13016| N307_09455| N310_04478| N320_08753| N326_06471| N330_10673| N332_12015| N333_03974| N335_00292| N339_04671| UY3_01190| Y1Q_025318| Z169_16298| hoxa10

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