The Function of HOXA10
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'.
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Protein names
Recommended name:
Homeobox protein Hox-A10Short name:
PLAlternative name(s):
Homeobox protein Hox-1.8Homeobox protein Hox-1H
Top Gene-Substance Interactions
HOXA10 Interacts with These Diseases
| Disease | Score |
Substances That Increase HOXA10
| Substances | Interaction | Organism | Category |
Substances That Decrease HOXA10
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Molecular Function:
- Histone Deacetylase Binding
- Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Dna Binding
- Transcriptional Activator Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding
Biological Processes:
- Anterior/Posterior Pattern Specification
- Embryonic Limb Morphogenesis
- Male Gonad Development
- Multicellular Organism Development
- Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
- Proximal/Distal Pattern Formation
- Single Fertilization
- Skeletal System Development
- Spermatogenesis
- Uterus Development