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  3. HIVEP2

HIVEP2 (Human immunodeficiency virus type I enhancer binding protein 2)

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The Function of HIVEP2

This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. It may act in T-cell activation.

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Protein names

Recommended name:

Transcription factor HIVEP2

Short name:

MBP-2

Alternative name(s):

Human immunodeficiency virus type I enhancer-binding protein 2
HIV-EP2
MHC-binding protein 2

HIVEP2 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS12211360 (HIVEP2) ??
  2. RS197480 (HIVEP2) ??

Top Gene-Substance Interactions

HIVEP2 Interacts with These Diseases

Disease Score

Substances That Increase HIVEP2

Substances Interaction Organism Category

Substances That Decrease HIVEP2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Pbx1a
  • MEF-2A
  • E4BP4
  • ATF6
  • NCX/Ncx

Tissue specificity:

Expressed in brain and skeletal muscle.

Induction:

By mitogens and phorbol ester.

Molecular Function:

  • Dna Binding
  • Metal Ion Binding
  • Sequence-Specific Dna Binding
  • Transcription Factor Activity, Sequence-Specific Dna Binding
  • Transcription Regulatory Region Dna Binding

Biological Processes:

  • Multicellular Organism Development
  • Regulation Of Transcription, Dna-Templated
  • Signal Transduction
  • Transcription From Rna Polymerase Ii Promoter
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_05676| Anapl_15901| angiotensinogen gene-inducible enhancer-binding protein 1| AS27_14797| AS28_03824| CB1_001107064| c-myc intron binding protein 1| D623_10035753| DNA-binding protein AGIE-BP1| H920_06357| HIV-EP2| human immunodeficiency virus type 1 enhancer-binding protein 2| human immunodeficiency virus type I enhancer-binding protein 2 homolog| immunodeficiency virus type I enhancer| immunodeficiency virus type I enhancer-binding 2-like protein| immunodeficiency virus type I enhancer-binding protein 2 homolog| immunodeficiency virus type I enhancer binding protein 2 isoform 1-like protein| M91_16253| M959_10303| MBP-2| MDA_GLEAN10018608| MHC binding protein-2| MIBP1| MIBP-1| MRD43| myc intron-binding protein 1| N300_09765| N301_01741| N302_13311| N303_10083| N305_02120| N306_12131| N307_13435| N308_07217| N309_12682| N311_03157| N312_01556| N320_13024| N321_11682| N322_09891| N324_12841| N325_07569| N326_08144| N327_10681| N328_02066| N329_00386| N330_01618| N331_00419| N332_00636| N333_12063| N334_02820| N335_12765| N336_05143| N339_01382| N340_01414| N341_04517| PAL_GLEAN10014023| PANDA_000411| schnurri 2| Schnurri-2| Shn-2| SHN2| transcription factor HIVEP2| TREES_T100019429| UY3_03689| Y1Q_020928| Y956_00305| Z169_09603| ZAS2| ZNF40B| hivep2

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