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  3. HIST1H1E

HIST1H1E (Histone cluster 1 H1 family member e)

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The Function of HIST1H1E

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.

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Protein names

Recommended name:

Histone H1.4

Alternative name(s):

Histone H1b
Histone H1s-4

HIST1H1E SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS198811 (HIST1H1E) ??
  2. RS4141885 (HIST1H1E) ??

Top Gene-Substance Interactions

Substances That Increase HIST1H1E

Substances Interaction Organism Category

Substances That Decrease HIST1H1E

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

Gene Pathways:

  • Cellular responses to stress
  • Apoptosis

Molecular Function:

  • Chromatin Dna Binding
  • Poly(A) Rna Binding

Biological Processes:

  • Histone H3-K27 Trimethylation
  • Histone H3-K4 Trimethylation
  • Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Nucleosome Assembly
  • Nucleosome Positioning
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

H1 histone family, member 4| H1s-4| histone H1.4| dJ221C16.5| H1-4| H1.4| H1E| H1F4| H1var2| H1 VAR.2| histone 1, H1e| histone cluster 1, H1e| histone H1b| histone H1e| histone H1s-4| hist1h1e

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