The Function of HIST1H1E
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
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Protein names
Recommended name:
Histone H1.4Alternative name(s):
Histone H1bHistone H1s-4
- RS198811 (HIST1H1E) ??
- RS4141885 (HIST1H1E) ??
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Top Gene-Substance Interactions
Substances That Increase HIST1H1E
| Substances | Interaction | Organism | Category |
Substances That Decrease HIST1H1E
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Histone H3-K27 Trimethylation
- Histone H3-K4 Trimethylation
- Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
- Nucleosome Assembly
- Nucleosome Positioning