• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. HAPLN1

HAPLN1 (Hyaluronan and proteoglycan link protein 1)

Loading...

Summary of HAPLN1

The gene codes for a protein, hyaluronan and proteoglycan link protein 1. It is on chromosome 5 [R].

0 users want this gene increased, 0 users want it decreased

The Function of HAPLN1

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.

Protein names

Recommended name:

Hyaluronan and proteoglycan link protein 1

Alternative name(s):

Cartilage-linking protein 1
Cartilage-link protein
Proteoglycan link protein

HAPLN1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS310501 (HAPLN1) ??
  2. RS3846635 (HAPLN1) ??
  3. RS4466137 (HAPLN1) ??
  4. RS4552569 (HAPLN1) ??

Top Gene-Substance Interactions

HAPLN1 Interacts with These Diseases

Disease Score

Substances That Increase HAPLN1

Substances Interaction Organism Category

Substances That Decrease HAPLN1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • p53
  • Sox9

Tissue specificity:

Widely expressed. Weakly expressed in the brain.

Gene Pathways:

  • Extracellular matrix organization

Molecular Function:

  • Extracellular Matrix Structural Constituent
  • Hyaluronic Acid Binding

Biological Processes:

  • Cell Adhesion
  • Central Nervous System Development
  • Extracellular Matrix Organization
  • Skeletal System Development
  • Mitophagy In Response To Mitochondrial Depolarization

Drug Bank:

  • Hyaluronic Acid
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| CLP| CTRL1| Anapl_07764| AS27_00734| AS28_04445| cartilage linking protein 1| cartilage-linking protein 1| cartilage-link protein| Cartilage link protein| Cartilage link protein 1| CB1_000373002| CRT1| Crtl1| Crtl1l| D623_10016486| EH28_13334| GW7_17142| H920_10788| link protein| link protein precursor (AA -15 to 339)| LP| LP-1| M959_04275| N300_13725| N301_05756| N302_09874| N303_08077| N305_07167| N306_04787| N307_08922| N311_04454| N312_06763| N320_04430| N321_10649| N322_10715| N324_04201| N325_07495| N326_08310| N327_11831| N330_04307| N331_03038| N332_13734| N334_11224| N335_11610| N336_08932| N339_01938| PAL_GLEAN10024955| PANDA_017570| proteoglycan link protein| TREES_T100019301| UY3_13357| Y1Q_016632| Y956_13603| Z169_01801| hapln1

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved