Protein names
Recommended name:
Guanylate cyclase soluble subunit alpha-3Alternative name(s):
GCS-alpha-3GCS-alpha-1
Soluble guanylate cyclase large subunit
- RS10019835 (GUCY1A3) ??
- RS13139571 (GUCY1A3) ??
- RS13143871 (GUCY1A3) ??
- RS1483035 (GUCY1A3) ??
- RS1842896 (GUCY1A3) ??
- RS72689147 (GUCY1A3) ??
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Top Gene-Substance Interactions
GUCY1A3 Interacts with These Diseases
| Disease | Score |
Substances That Increase GUCY1A3
| Substances | Interaction | Organism | Category |
Substances That Decrease GUCY1A3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Detected in brain cortex and lung (at protein level).
Gene Pathways:
Enzyme Regulation:
Activated by nitric oxide in the presence of magnesium or manganese ions.
Cofactor:
Has also activity with Mn(2+) (in vitro).
Molecular Function:
Biological Processes:
- Cgmp Biosynthetic Process
- Nitric Oxide Mediated Signal Transduction
- Blood Circulation
- Regulation Of Blood Pressure
- Response To Herbicide
- Response To Organic Cyclic Compound
- Positive Regulation Of Cgmp Biosynthetic Process
- Response To Defense-Related Host Nitric Oxide Production
- Relaxation Of Vascular Smooth Muscle