Summary of GSTA2
The gene codes for a protein, glutathione S-transferase alpha 2. Variations can affect the toxicity and effectiveness of some drugs [R].
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The Function of GSTA2
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Protein names
Recommended name:
Glutathione S-transferase A2Short name:
GTH2Alternative name(s):
GST HA subunit 2GST class-alpha member 2
GST-gamma
GSTA2-2
- RS2180314 (GSTA2) ??
- RS2234951 (GSTA2) ??
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Top Gene-Substance Interactions
GSTA2 Interacts with These Diseases
Disease | Score |
Substances That Increase GSTA2
Substances | Interaction | Organism | Category |
Substances That Decrease GSTA2
Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Liver.
Gene Pathways:
Molecular Function:
Biological Processes:
- Epithelial Cell Differentiation
- Glutathione Derivative Biosynthetic Process
- Glutathione Metabolic Process