Substances	Interaction	Organism	Category

Substances	Interaction	Organism	Category

Condition	Change (log2fold)	Comparison	Species	Experimental variables	Experiment name

Condition	Change (log2fold)	Comparison	Species	Experimental variables	Experiment name

The following transcription factors affect gene expression:

Tissue specificity:

Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach.

Induction:

By all-trans retinoic acid (ATRA).

Caution:

It is uncertain whether Met-1 or Met-9 is the initiator.

Molecular Function:

• G-Protein Coupled Receptor Activity
• G-Protein Coupled Receptor Binding
• Protein Kinase Binding

Biological Processes:

• Glucose Homeostasis
• Locomotory Behavior
• Positive Regulation Of Canonical Wnt Signaling Pathway
• Positive Regulation Of I-Kappab Kinase/Nf-Kappab Signaling
• Positive Regulation Of Inflammatory Response
• Positive Regulation Of Macrophage Cytokine Production
• Positive Regulation Of Neuron Differentiation
• Positive Regulation Of Neuron Projection Development
• Positive Regulation Of Protein Tyrosine Kinase Activity

*synonyms