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  3. GPAM

GPAM (Glycerol-3-phosphate acyltransferase, mitochondrial)

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The Function of GPAM

Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.

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Protein names

Recommended name:

Glycerol-3-phosphate acyltransferase 1, mitochondrial

Short name:

GPAT-1

GPAM SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS1129555 (GPAM) ??
  2. RS2255141 (GPAM) ??
  3. RS2297991 (GPAM) ??
  4. RS77147124 (GPAM) ??

Top Gene-Substance Interactions

GPAM Interacts with These Diseases

Disease Score

Substances That Increase GPAM

Substances Interaction Organism Category

Substances That Decrease GPAM

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-alpha
  • MEF-2A
  • IRF-1
  • Lmo2
  • Nkx5-1
  • FOXL1

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Glycerophospholipid metabolism
  • Glycerolipid metabolism

Molecular Function:

  • Glycerol-3-Phosphate O-Acyltransferase Activity

Biological Processes:

  • Acyl-Coa Metabolic Process
  • Cdp-Diacylglycerol Biosynthetic Process
  • Defense Response To Virus
  • Fatty Acid Homeostasis
  • Fatty Acid Metabolic Process
  • Interleukin-2 Secretion
  • Negative Regulation Of Activation-Induced Cell Death Of T Cells
  • Phosphatidic Acid Biosynthetic Process
  • Phospholipid Homeostasis
  • Positive Regulation Of Activated T Cell Proliferation
  • Positive Regulation Of Multicellular Organism Growth
  • Regulation Of Cytokine Secretion
  • Response To Glucose
  • Triglyceride Biosynthetic Process
  • Cellular Response To Insulin Stimulus
  • Positive Regulation Of Triglyceride Biosynthetic Process
  • Response To Cadmium Ion
  • Response To Fructose
  • Response To Nutrient Levels
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| P90| A306_04162| AS27_02766| CB1_000678044| D623_10027949| glyceraldehyde-3-phosphate acyltransferase| glycerol-3-phosphate acyltransferase| Glycerol-3-phosphate acyltransferase 1| glycerol-3-phosphate acyltransferase 1, mitochondrial| glycerol-3-phosphate acyltransferase 1, mitochondrial-like protein| gpat| gpat1| GPAT-1| GW7_14635| H920_09640| M91_07881| mitochondrial glycerol 3-phosphate acyltransferase| mitochondrial glycerol phosphate acyltransferase| mtGPAT| N300_04618| N301_07039| N303_05187| N306_03419| N308_15755| N309_05032| N312_12763| N320_11690| N321_13938| N322_02115| N324_12764| N326_01751| N327_06658| N328_01818| N330_01526| N332_00520| N333_11874| N335_09940| N336_07897| N339_03789| N340_12977| N341_07110| PAL_GLEAN10014188| PANDA_001421| TREES_T100019530| uncharacterized protein MGC145183| UY3_03770| Y1Q_005129| Y956_01359| Z169_15487| gpam

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