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  3. GDF10

GDF10 (Growth differentiation factor 10)

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The Function of GDF10

Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis.

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Protein names

Recommended name:

Growth/differentiation factor 10

Short name:

BIP

Alternative name(s):

GDF-10
Bone morphogenetic protein 3B
BMP-3B
Bone-inducing protein

GDF10 SNPs

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  1. RS9421748 (GDF10) ??

Top Gene-Substance Interactions

Substances That Increase GDF10

Substances Interaction Organism Category

Substances That Decrease GDF10

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • HNF-4alpha1
  • HNF-4alpha2

Tissue specificity:

Expressed in femur, brain, lung, skeletal muscle, pancreas and testis.

Molecular Function:

  • Cytokine Activity
  • Growth Factor Activity
  • Transforming Growth Factor Beta Receptor Binding

Biological Processes:

  • Bmp Signaling Pathway
  • Cell Development
  • Fat Cell Differentiation
  • Negative Regulation Of Osteoblast Differentiation
  • Osteoblast Differentiation
  • Positive Regulation Of Pathway-Restricted Smad Protein Phosphorylation
  • Regulation Of Apoptotic Process
  • Regulation Of Mapk Cascade
  • Skeletal System Development
  • Smad Protein Signal Transduction
  • Transforming Growth Factor Beta Receptor Signaling Pathway
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_03956| AS27_02580| AS28_04487| BIP| bmp3b| bmp-3b| bone-inducing protein| bone morphogenetic protein 3b| CB1_002401003| D623_10008746| gdf-10| growth/differentiation factor 10| GW7_07237| M959_03214| MDA_GLEAN10013115| N300_07528| N301_10670| N302_13464| N303_09214| N305_11436| N306_10139| N307_06117| N308_09063| N309_08246| N310_07358| N311_10497| N320_04199| N321_13319| N324_09855| N325_02570| N326_09525| N327_13901| N328_07869| N330_10683| N331_01110| N332_10788| N334_10861| N335_06680| N336_09576| N339_01617| N340_03152| PAL_GLEAN10004411| PANDA_020471| prepro bone inducing protein| TREES_T100013933| UY3_15892| Y956_01543| Z169_12786| gdf10

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