The Function of GAS2
May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process.
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Protein names
Recommended name:
Growth arrest-specific protein 2Short name:
GAS-2- RS7111546 (GAS2) ??
- RS712022 (GAS2) ??
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Top Gene-Substance Interactions
Substances That Increase GAS2
| Substances | Interaction | Organism | Category |
Substances That Decrease GAS2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen.
Gene Pathways:
Developmental stage:
Specifically expressed at growth arrest.