• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. FTH1

FTH1 (Ferritin heavy chain 1)

Loading...

The Function of FTH1

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Ferritin heavy chain

Alternative name(s):

Ferritin H subunit
Cell proliferation-inducing gene 15 protein

Top Gene-Substance Interactions

FTH1 Interacts with These Diseases

Disease Score

Substances That Increase FTH1

Substances Interaction Organism Category

Substances That Decrease FTH1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • STAT1
  • STAT1beta
  • STAT1alpha

Tissue specificity:

Expressed in the liver.

Gene Pathways:

  • Membrane Trafficking
  • Transmembrane transport of small molecules
  • Mineral absorption
  • Porphyrin and chlorophyll metabolism

Molecular Function:

  • Ferric Iron Binding
  • Ferroxidase Activity
  • Iron Ion Binding

Biological Processes:

  • Cellular Iron Ion Homeostasis
  • Immune Response
  • Intracellular Sequestering Of Iron Ion
  • Iron Ion Import
  • Negative Regulation Of Cell Proliferation
  • Negative Regulation Of Fibroblast Proliferation
  • Iron Ion Transport

Drug Bank:

  • Iron Dextran
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| Ferritin heavy chain| MFH| apoferritin| AS27_05082| AS28_03746| CB1_000089023| cell proliferation-inducing gene 15 protein| D623_10005310| ferritin| ferritin H chain| ferritin heavy chain-like| Ferritin heavy chain, oocyte isoform| ferritin heavy polypeptide 1| ferritin, heavy polypeptide 1| ferritin, heavy subunit| Ferritin H subunit| Ferritin subunit H| FHC| FTH| fth1-a| fth1-b| FTHL6| H920_09075| HFE5| H-ferritin| HFt| M91_15488| M959_09259| N300_02446| N301_01142| N302_08634| N303_04061| N305_09599| N306_08436| N307_13542| N308_13421| N320_08484| N321_10253| N324_12923| N326_06385| N335_04817| N339_09721| N340_09188| PAL_GLEAN10011491| PANDA_015907| PIG15| placenta immunoregulatory factor| plif| proliferation-inducing protein 15| putative ferritin heavy chain| TREES_T100002296| UY3_10836| Y1Q_018265| Y956_04471| Z169_16528| fth1

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved