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  3. FRY

FRY (FRY microtubule binding protein)

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The Function of FRY

Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation.

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Protein names

Recommended name:

Protein furry homolog

FRY SNPs

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  1. RS7331540 (FRY) ??
  2. RS9533282 (FRY) ??

Top Gene-Substance Interactions

FRY Interacts with These Diseases

Disease Score

Substances That Increase FRY

Substances Interaction Organism Category

Substances That Decrease FRY

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • FOXO3
  • FOXO3a
  • GR
  • GR-alpha
  • FOXO1a
  • GATA-1
  • FOXF2
  • FOXO1
  • FOXC1
  • FOXO3b

Molecular Function:

  • Enzyme Inhibitor Activity

Biological Processes:

  • Actin Filament Reorganization
  • Cell Morphogenesis
  • Negative Regulation Of Tubulin Deacetylation
  • Neuron Projection Development
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| 60S ribosomal protein L6| 13CDNA73| 214K23.2| A306_11806| AF346502| bA207N4.2| bA37E23.1| C13orf14| C87180| CB1_002528005| CG32045 gene product from transcript CG32045-RB| CG32045-PB| CG32045-PC| CG32045-PE| CG32045-PF| CG32045-PG| CG32045-PH| CG32045-PI| CG32045-PJ| D623_10026475| D930046M03| Dmel_CG32045| EGK_09223| fry-PB| fry-PC| fry-PE| fry-PF| fry-PG| fry-PH| fry-PI| fry-PJ| furry| furry homolog| furry homolog (Drosophila)| furry-like protein| H920_05256| I79_011839| M91_09939| N339_06230| PAL_GLEAN10006783| PANDA_002721| protein furry| protein furry homolog| Protein furry-like| Protein furry like protein| Protein furry-like protein| RE-B| RGD1307034| SS3-7| suppressor of GMR-sina 3-7| TREES_T100014365| UY3_12832| WUGSC:H_2G3A.1| Xfurry| Y1Q_018572| yeti| fry

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