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  3. FLOT1

FLOT1 (Flotillin 1)

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Summary of FLOT1

This gene encodes a protein that plays a role in vesicle trafficking and the shape of a cell (R).

0 users want this gene increased, 0 users want it decreased

The Function of FLOT1

May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.

Protein names

Recommended name:

Flotillin-1

FLOT1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10947089 (FLOT1) ??
  2. RS3130660 (FLOT1) ??
  3. RS3909184 (FLOT1) ??

Top Gene-Substance Interactions

Substances That Increase FLOT1

Substances Interaction Organism Category

Substances That Decrease FLOT1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Pax-2

Gene Pathways:

  • Insulin signaling pathway

Molecular Function:

  • Protease Binding
  • Protein Heterodimerization Activity

Biological Processes:

  • Axonogenesis
  • Cellular Response To Exogenous Dsrna
  • Dsrna Transport
  • Establishment Of Protein Localization To Plasma Membrane
  • Extracellular Matrix Disassembly
  • Membrane Raft Assembly
  • Plasma Membrane Raft Assembly
  • Positive Regulation Of Cell Adhesion Molecule Production
  • Positive Regulation Of Cell-Cell Adhesion Mediated By Cadherin
  • Positive Regulation Of Cell Junction Assembly
  • Positive Regulation Of Cytokine Production
  • Positive Regulation Of Endocytosis
  • Positive Regulation Of Heterotypic Cell-Cell Adhesion
  • Positive Regulation Of Interferon-Beta Production
  • Positive Regulation Of Myoblast Fusion
  • Positive Regulation Of Protein Phosphorylation
  • Positive Regulation Of Skeletal Muscle Tissue Development
  • Positive Regulation Of Synaptic Transmission, Dopaminergic
  • Positive Regulation Of Toll-Like Receptor 3 Signaling Pathway
  • Protein Homooligomerization
  • Protein Kinase C Signaling
  • Protein Localization To Membrane Raft
  • Regulation Of Receptor Internalization
  • Regulation Of Rho Protein Signal Transduction
  • Response To Endoplasmic Reticulum Stress
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| CB1_001562017| D623_10004992| EGK_14682| flot1-a| flot1-b| flotillin1| flotillin-1| GW7_04754| H920_13535| I79_013152| integral membrane component of caveolae| PAL_GLEAN10001344| PANDA_018957| Rareg| REG-2| reggie-2| reggie protein 2b| UY3_18347| Y1Q_025674| flot1

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