The Function of FILIP1
By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A.
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Protein names
Recommended name:
Filamin-A-interacting protein 1Short name:
FILIP- RS12209223 (FILIP1) ??
- RS9360921 (FILIP1) ??
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Top Gene-Substance Interactions
FILIP1 Interacts with These Diseases
| Disease | Score |
Substances That Increase FILIP1
| Substances | Interaction | Organism | Category |
Substances That Decrease FILIP1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus.
*synonyms