The Function of FGF9
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Fibroblast growth factor 9Short name:
GAFAlternative name(s):
FGF-9Glia-activating factor
Heparin-binding growth factor 9
HBGF-9
- RS518590 (FGF9) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
FGF9 Interacts with These Diseases
| Disease | Score |
Substances That Increase FGF9
| Substances | Interaction | Organism | Category |
Substances That Decrease FGF9
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Glial cells.
Gene Pathways:
Molecular Function:
- 1-Phosphatidylinositol-3-Kinase Activity
- Growth Factor Activity
- Heparin Binding
- Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Activity
- Protein Tyrosine Kinase Activity
- Ras Guanyl-Nucleotide Exchange Factor Activity
Biological Processes:
- Angiogenesis
- Cell-Cell Signaling
- Chondrocyte Differentiation
- Embryonic Digestive Tract Development
- Embryonic Limb Morphogenesis
- Embryonic Skeletal System Development
- Eye Development
- Fibroblast Growth Factor Receptor Signaling Pathway
- Inner Ear Morphogenesis
- Lung-Associated Mesenchyme Development
- Male Gonad Development
- Male Sex Determination
- Mapk Cascade
- Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
- Negative Regulation Of Wnt Signaling Pathway
- Osteoblast Differentiation
- Phosphatidylinositol-Mediated Signaling
- Positive Regulation Of Activin Receptor Signaling Pathway
- Positive Regulation Of Canonical Wnt Signaling Pathway
- Positive Regulation Of Cardiac Muscle Cell Proliferation
- Positive Regulation Of Cell Division
- Positive Regulation Of Cell Proliferation
- Positive Regulation Of Epithelial Cell Proliferation
- Positive Regulation Of Gene Expression
- Positive Regulation Of Mapk Cascade
- Positive Regulation Of Mesenchymal Cell Proliferation
- Positive Regulation Of Smoothened Signaling Pathway
- Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
- Protein Import Into Nucleus
- Regulation Of Phosphatidylinositol 3-Kinase Signaling
- Regulation Of Timing Of Cell Differentiation
- Signal Transduction
- Substantia Nigra Development