The Function of FGF6
Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Fibroblast growth factor 6Short name:
FGF-6Alternative name(s):
Heparin secretory-transforming protein 2HST-2
HSTF-2
Heparin-binding growth factor 6
HBGF-6
- RS10849061 (FGF6) ??
- RS888468 (FGF6) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
Substances That Increase FGF6
| Substances | Interaction | Organism | Category |
Substances That Decrease FGF6
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Leukemia cell lines with platelet/ megakaryocytic differentiation potential.
Gene Pathways:
Molecular Function:
- Protein Tyrosine Kinase Activity
- Ras Guanyl-Nucleotide Exchange Factor Activity
- Growth Factor Activity
- 1-Phosphatidylinositol-3-Kinase Activity
- Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Activity
Biological Processes:
- Mapk Cascade
- Cartilage Condensation
- Angiogenesis
- Signal Transduction
- Cell-Cell Signaling
- Cell Proliferation
- Positive Regulation Of Cell Proliferation
- Fibroblast Growth Factor Receptor Signaling Pathway
- Regulation Of Phosphatidylinositol 3-Kinase Signaling
- Myoblast Differentiation
- Phosphatidylinositol-Mediated Signaling
- Positive Regulation Of Cell Division