The Function of FGF6
Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.
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Protein names
Recommended name:
Fibroblast growth factor 6Short name:
FGF-6Alternative name(s):
Heparin secretory-transforming protein 2HST-2
HSTF-2
Heparin-binding growth factor 6
HBGF-6
- RS10849061 (FGF6) ??
- RS888468 (FGF6) ??
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Top Gene-Substance Interactions
Substances That Increase FGF6
| Substances | Interaction | Organism | Category |
Substances That Decrease FGF6
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Leukemia cell lines with platelet/ megakaryocytic differentiation potential.
Gene Pathways:
Molecular Function:
- 1-Phosphatidylinositol-3-Kinase Activity
- Growth Factor Activity
- Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Activity
- Protein Tyrosine Kinase Activity
- Ras Guanyl-Nucleotide Exchange Factor Activity
Biological Processes:
- Angiogenesis
- Cartilage Condensation
- Cell-Cell Signaling
- Cell Proliferation
- Fibroblast Growth Factor Receptor Signaling Pathway
- Mapk Cascade
- Myoblast Differentiation
- Phosphatidylinositol-Mediated Signaling
- Positive Regulation Of Cell Division
- Positive Regulation Of Cell Proliferation
- Regulation Of Phosphatidylinositol 3-Kinase Signaling
- Signal Transduction