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  3. FGF6

FGF6 (Fibroblast growth factor 6)

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The Function of FGF6

Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.

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Protein names

Recommended name:

Fibroblast growth factor 6

Short name:

FGF-6

Alternative name(s):

Heparin secretory-transforming protein 2
HST-2
HSTF-2
Heparin-binding growth factor 6
HBGF-6

FGF6 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10849061 (FGF6) ??
  2. RS888468 (FGF6) ??

Top Gene-Substance Interactions

Substances That Increase FGF6

Substances Interaction Organism Category

Substances That Decrease FGF6

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • c-Jun
  • MEF-2A
  • Hlf
  • c-Myc
  • E4BP4

Tissue specificity:

Leukemia cell lines with platelet/ megakaryocytic differentiation potential.

Gene Pathways:

  • Disease
  • Immune System
  • MAPK signaling pathway
  • Melanoma
  • Pathways in cancer
  • Regulation of actin cytoskeleton
  • Signal Transduction

Molecular Function:

  • 1-Phosphatidylinositol-3-Kinase Activity
  • Growth Factor Activity
  • Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Activity
  • Protein Tyrosine Kinase Activity
  • Ras Guanyl-Nucleotide Exchange Factor Activity

Biological Processes:

  • Angiogenesis
  • Cartilage Condensation
  • Cell-Cell Signaling
  • Cell Proliferation
  • Fibroblast Growth Factor Receptor Signaling Pathway
  • Mapk Cascade
  • Myoblast Differentiation
  • Phosphatidylinositol-Mediated Signaling
  • Positive Regulation Of Cell Division
  • Positive Regulation Of Cell Proliferation
  • Regulation Of Phosphatidylinositol 3-Kinase Signaling
  • Signal Transduction
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| AS27_14189| AS28_12994| CB1_000216050| D623_10028698| Fgf-6| fibroblast growth factor 6-like protein| H920_18347| hbgf-6| heparin-binding growth factor 6| heparin secretory-transforming protein 2| HST2| HST-2| HSTF-2| I79_001364| M959_04906| MDA_GLEAN10008732| N300_02594| N301_03030| N302_05164| N303_06053| N305_07544| N306_14444| N307_04948| N310_13935| N311_01668| N312_12291| N320_12077| N321_12783| N322_03361| N324_12695| N325_05556| N327_13277| N328_01026| N329_08774| N330_07664| N331_03671| N332_12696| N333_01461| N334_04315| N336_04825| N340_14602| N341_03292| PAL_GLEAN10022487| PANDA_009226| TREES_T100006097| UY3_03085| Y1Q_014743| Y956_15991| Z169_06942| fgf6

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