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  3. FGF18

FGF18 (Fibroblast growth factor 18)

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The Function of FGF18

Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.

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Protein names

Recommended name:

Fibroblast growth factor 18

Alternative name(s):

FGF-18
zFGF5

FGF18 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS4620037 (FGF18) ??

Top Gene-Substance Interactions

Substances That Increase FGF18

Substances Interaction Organism Category

Substances That Decrease FGF18

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • HNF-4alpha1
  • HNF-4alpha2
  • STAT1
  • STAT1beta
  • STAT1alpha

Gene Pathways:

  • Disease
  • Immune System
  • MAPK signaling pathway
  • Melanoma
  • Pathways in cancer
  • Regulation of actin cytoskeleton
  • Signal Transduction

Molecular Function:

  • 1-Phosphatidylinositol-3-Kinase Activity
  • Growth Factor Activity
  • Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Activity
  • Protein Tyrosine Kinase Activity
  • Ras Guanyl-Nucleotide Exchange Factor Activity
  • Type 1 Fibroblast Growth Factor Receptor Binding
  • Type 2 Fibroblast Growth Factor Receptor Binding

Biological Processes:

  • Anatomical Structure Morphogenesis
  • Angiogenesis
  • Cell-Cell Signaling
  • Chondrocyte Development
  • Endochondral Ossification
  • Fibroblast Growth Factor Receptor Signaling Pathway
  • Intramembranous Ossification
  • Lung Development
  • Mapk Cascade
  • Phosphatidylinositol-Mediated Signaling
  • Positive Regulation Of Cell Proliferation
  • Positive Regulation Of Chondrocyte Differentiation
  • Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor
  • Positive Regulation Of Erk1 And Erk2 Cascade
  • Positive Regulation Of Map Kinase Activity
  • Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
  • Regulation Of Phosphatidylinositol 3-Kinase Signaling
  • Signal Transduction
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_14701| AS27_11833| AS28_06025| D623_10024111| FGF-18| H920_04459| M91_07513| M959_11899| MDA_GLEAN10021389| N300_13086| N301_15663| N302_13655| N303_10648| N305_03633| N306_11856| N307_10014| N308_13096| N309_02628| N310_03198| N311_07482| N312_00868| N320_02099| N322_00681| N324_11033| N325_08036| N326_04921| N329_08323| N330_13460| N331_01716| N334_09422| N339_10106| N340_13338| PAL_GLEAN10018880| PANDA_011965| TREES_T100014779| UY3_18210| Y1Q_013196| Y956_14146| Z169_13550| ZFGF5| fgf18

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