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  3. FGF10

FGF10 (Fibroblast growth factor 10)

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The Function of FGF10

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing.

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Protein names

Recommended name:

Fibroblast growth factor 10

Short name:

FGF-10

Alternative name(s):

Keratinocyte growth factor 2

FGF10 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS2121875 (FGF10) ??
  2. RS4296809 (FGF10) ??

Top Gene-Substance Interactions

FGF10 Interacts with These Diseases

Disease Score

Substances That Increase FGF10

Substances Interaction Organism Category

Substances That Decrease FGF10

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • AP-1
  • c-Jun
  • C/EBPalpha
  • Nkx3-1 v1
  • Nkx3-1
  • FOXC1

Gene Pathways:

  • Disease
  • Immune System
  • MAPK signaling pathway
  • Melanoma
  • Pathways in cancer
  • Regulation of actin cytoskeleton
  • Signal Transduction

Molecular Function:

  • 1-Phosphatidylinositol-3-Kinase Activity
  • Chemoattractant Activity
  • Fibroblast Growth Factor Receptor Binding
  • Growth Factor Activity
  • Heparin Binding
  • Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Activity
  • Protein Tyrosine Kinase Activity
  • Ras Guanyl-Nucleotide Exchange Factor Activity
  • Type 2 Fibroblast Growth Factor Receptor Binding

Biological Processes:

  • Actin Cytoskeleton Reorganization
  • Activation Of Mapk Activity
  • Angiogenesis
  • Blood Vessel Remodeling
  • Branch Elongation Involved In Salivary Gland Morphogenesis
  • Branching Morphogenesis Of An Epithelial Tube
  • Bronchiole Morphogenesis
  • Bud Elongation Involved In Lung Branching
  • Bud Outgrowth Involved In Lung Branching
  • Determination Of Left/Right Symmetry
  • Embryonic Camera-Type Eye Development
  • Embryonic Digestive Tract Morphogenesis
  • Embryonic Genitalia Morphogenesis
  • Embryonic Pattern Specification
  • Epithelial Cell Migration
  • Epithelial Cell Proliferation
  • Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis
  • Erk1 And Erk2 Cascade
  • Establishment Of Mitotic Spindle Orientation
  • Female Genitalia Morphogenesis
  • Fibroblast Growth Factor Receptor Signaling Pathway
  • Fibroblast Growth Factor Receptor Signaling Pathway Involved In Mammary Gland Specification
  • Hair Follicle Morphogenesis
  • Harderian Gland Development
  • Induction Of Positive Chemotaxis
  • Keratinocyte Proliferation
  • Lacrimal Gland Development
  • Limb Bud Formation
  • Lung Epithelium Development
  • Lung Proximal/Distal Axis Specification
  • Lung Saccule Development
  • Male Genitalia Morphogenesis
  • Mammary Gland Bud Formation
  • Mapk Cascade
  • Mesenchymal Cell Differentiation Involved In Lung Development
  • Mesenchymal-Epithelial Cell Signaling Involved In Lung Development
  • Mesonephros Development
  • Metanephros Development
  • Metanephros Morphogenesis
  • Muscle Cell Fate Commitment
  • Negative Regulation Of Cell Cycle Arrest
  • Negative Regulation Of Cell Differentiation
  • Negative Regulation Of Cell Proliferation
  • Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
  • Odontogenesis Of Dentin-Containing Tooth
  • Organ Induction
  • Otic Vesicle Formation
  • Pancreas Development
  • Phosphatidylinositol-Mediated Signaling
  • Pituitary Gland Development
  • Positive Chemotaxis
  • Positive Regulation Of Atpase Activity
  • Positive Regulation Of Canonical Wnt Signaling Pathway
  • Positive Regulation Of Cyclin-Dependent Protein Serine/Threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle
  • Positive Regulation Of Dna Repair
  • Positive Regulation Of Dna Replication
  • Positive Regulation Of Epithelial Cell Migration
  • Positive Regulation Of Epithelial Cell Proliferation
  • Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing
  • Positive Regulation Of Erk1 And Erk2 Cascade
  • Positive Regulation Of Fibroblast Proliferation
  • Positive Regulation Of Hair Follicle Cell Proliferation
  • Positive Regulation Of Keratinocyte Migration
  • Positive Regulation Of Keratinocyte Proliferation
  • Positive Regulation Of Lymphocyte Proliferation
  • Positive Regulation Of Mapk Cascade
  • Positive Regulation Of Mitotic Cell Cycle
  • Positive Regulation Of Notch Signaling Pathway
  • Positive Regulation Of Peptidyl-Tyrosine Phosphorylation
  • Positive Regulation Of Ras Protein Signal Transduction
  • Positive Regulation Of Transcription, Dna-Templated
  • Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Positive Regulation Of Urothelial Cell Proliferation
  • Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
  • Positive Regulation Of White Fat Cell Proliferation
  • Prostatic Bud Formation
  • Protein Localization To Cell Surface
  • Radial Glial Cell Differentiation
  • Regulation Of Activin Receptor Signaling Pathway
  • Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-Epithelial Signaling
  • Regulation Of Phosphatidylinositol 3-Kinase Signaling
  • Regulation Of Saliva Secretion
  • Regulation Of Smoothened Signaling Pathway
  • Response To Estradiol
  • Response To Lipopolysaccharide
  • Salivary Gland Development
  • Secretion By Lung Epithelial Cell Involved In Lung Growth
  • Semicircular Canal Fusion
  • Smooth Muscle Cell Differentiation
  • Somatic Stem Cell Population Maintenance
  • Spleen Development
  • Submandibular Salivary Gland Formation
  • Tear Secretion
  • Thymus Development
  • Thyroid Gland Development
  • Tissue Regeneration
  • Type Ii Pneumocyte Differentiation
  • Urothelial Cell Proliferation
  • White Fat Cell Differentiation
  • Wound Healing
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_05161| AEY17| AS27_03880| AS28_07958| D623_10029765| EGK_16462| FGF| Fgf-10| fibroblast growth factor 10 (FGF10) homologue| Gsfaey17| GW7_16852| H920_07773| keratinocyte growth factor 2| M959_11601| MDA_GLEAN10024091| N300_13503| N302_10551| N303_14241| N305_06127| N306_15502| N307_00673| N322_10523| obg-like ATPase 1| PAL_GLEAN10009643| PANDA_015056| produced by fibroblasts of urinary bladder lamina propria| PsFGF10| TREES_T100002267| UY3_00339| Y1Q_013181| Z169_14816| fgf10

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