Summary of FGD6
This gene encodes a protein that plays a role in cell shape and the cytoskeleton (R).
0 users want this gene increased,
0 users want it decreased
The Function of FGD6
May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape.
Protein names
Recommended name:
FYVE, RhoGEF and PH domain-containing protein 6Alternative name(s):
Zinc finger FYVE domain-containing protein 24- RS10507047 (FGD6) ??
- RS12310399 (FGD6) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
Substances That Increase FGD6
| Substances | Interaction | Organism | Category |
Substances That Decrease FGD6
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Molecular Function:
- Guanyl-Nucleotide Exchange Factor Activity
- Rho Guanyl-Nucleotide Exchange Factor Activity
- Small Gtpase Binding
- Metal Ion Binding
Biological Processes:
- Cytoskeleton Organization
- Regulation Of Cell Shape
- Actin Cytoskeleton Organization
- Regulation Of Rho Protein Signal Transduction
- Regulation Of Gtpase Activity
- Filopodium Assembly