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  3. FGD6

FGD6 (FYVE, RhoGEF and PH domain containing 6)

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Summary of FGD6

This gene encodes a protein that plays a role in cell shape and the cytoskeleton (R).

0 users want this gene increased, 0 users want it decreased

The Function of FGD6

May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape.

Protein names

Recommended name:

FYVE, RhoGEF and PH domain-containing protein 6

Alternative name(s):

Zinc finger FYVE domain-containing protein 24

FGD6 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10507047 (FGD6) ??
  2. RS12310399 (FGD6) ??

Top Gene-Substance Interactions

Substances That Increase FGD6

Substances Interaction Organism Category

Substances That Decrease FGD6

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Evi-1
  • PPAR-gamma1
  • PPAR-gamma2
  • Pax-3
  • FOXO1a
  • FOXO1
  • Cdc5
  • FOXC1
  • NCX/Ncx

Molecular Function:

  • Guanyl-Nucleotide Exchange Factor Activity
  • Metal Ion Binding
  • Rho Guanyl-Nucleotide Exchange Factor Activity
  • Small Gtpase Binding

Biological Processes:

  • Actin Cytoskeleton Organization
  • Cytoskeleton Organization
  • Filopodium Assembly
  • Regulation Of Cell Shape
  • Regulation Of Gtpase Activity
  • Regulation Of Rho Protein Signal Transduction
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_14864| AS27_09633| AS28_05593| CB1_000450002| D623_10008266| ethanol decreased 4| Etohd4| FYVE, RhoGEF and PH domain-containing protein 6| H920_07449| M91_16244| M959_11170| N300_06660| N301_14717| N302_12872| N303_04482| N305_08170| N306_04228| N307_03968| N308_05448| N310_03959| N311_01592| N312_07737| N320_02662| N324_07109| N325_12867| N328_05180| N330_07071| N333_10814| N334_08152| N340_08628| PAL_GLEAN10015530| PANDA_007908| RGD1565609| TREES_T100009228| UY3_16003| Y1Q_022202| Y956_04052| Z169_09280| ZFYVE24| zinc finger FYVE domain-containing protein 24| fgd6

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