Summary of FGD6
This gene encodes a protein that plays a role in cell shape and the cytoskeleton (R).
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The Function of FGD6
May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape.
Protein names
Recommended name:
FYVE, RhoGEF and PH domain-containing protein 6Alternative name(s):
Zinc finger FYVE domain-containing protein 24- RS10507047 (FGD6) ??
- RS12310399 (FGD6) ??
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Top Gene-Substance Interactions
Substances That Increase FGD6
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Substances That Decrease FGD6
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Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Molecular Function:
- Guanyl-Nucleotide Exchange Factor Activity
- Metal Ion Binding
- Rho Guanyl-Nucleotide Exchange Factor Activity
- Small Gtpase Binding
Biological Processes:
- Actin Cytoskeleton Organization
- Cytoskeleton Organization
- Filopodium Assembly
- Regulation Of Cell Shape
- Regulation Of Gtpase Activity
- Regulation Of Rho Protein Signal Transduction