The Function of FABP5
High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
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Protein names
Recommended name:
Fatty acid-binding protein, epidermalShort name:
E-FABPAlternative name(s):
Epidermal-type fatty acid-binding proteinFatty acid-binding protein 5
Psoriasis-associated fatty acid-binding protein homolog
PA-FABP
- RS12216812 (FABP5) ??
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Top Gene-Substance Interactions
FABP5 Interacts with These Diseases
| Disease | Score |
Substances That Increase FABP5
| Substances | Interaction | Organism | Category |
Substances That Decrease FABP5
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Keratinocytes; highly expressed in psoriatic skin.
Gene Pathways:
Molecular Function:
Biological Processes:
- Epidermis Development
- Glucose Metabolic Process
- Glucose Transport
- Lipid Metabolic Process
- Phosphatidylcholine Biosynthetic Process
- Response To Wounding
- Triglyceride Catabolic Process