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  3. FABP5

FABP5 (Fatty acid binding protein 5)

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The Function of FABP5

High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.

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Protein names

Recommended name:

Fatty acid-binding protein, epidermal

Short name:

E-FABP

Alternative name(s):

Epidermal-type fatty acid-binding protein
Fatty acid-binding protein 5
Psoriasis-associated fatty acid-binding protein homolog
PA-FABP

FABP5 SNPs

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  1. RS12216812 (FABP5) ??

Top Gene-Substance Interactions

FABP5 Interacts with These Diseases

Disease Score

Substances That Increase FABP5

Substances Interaction Organism Category

Substances That Decrease FABP5

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Evi-1
  • HNF-1A
  • HNF-1
  • C/EBPalpha
  • STAT5A
  • Pax-2

Tissue specificity:

Keratinocytes; highly expressed in psoriatic skin.

Gene Pathways:

  • PPAR signaling pathway

Molecular Function:

  • Fatty Acid Binding
  • Lipid Binding
  • Transporter Activity

Biological Processes:

  • Epidermis Development
  • Glucose Metabolic Process
  • Glucose Transport
  • Lipid Metabolic Process
  • Phosphatidylcholine Biosynthetic Process
  • Response To Wounding
  • Triglyceride Catabolic Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| Myelin P2 protein| CB1_002519014| C-FABP| cutaneous fatty acid-binding protein| DA11| differentiation-associated lipid-binding protein LP2| EFABP| E-FABP| EGK_19073| epidermal fatty acid-binding protein| Epidermal-type fatty acid-binding protein| epithelial fatty acid-binding protein| FABP5L2| FABP5L7| Fabpe| fatty acid-binding protein 5| fatty acid binding protein 5, epidermal| fatty acid binding protein 5-like| fatty acid binding protein 5-like 2| fatty acid binding protein 5-like 7| fatty acid binding protein 5 (psoriasis-associated)| fatty acid-binding protein, epidermal| fatty acid-binding protein, epidermal-like protein| H920_10383| I79_018329| keratinocyte lipid-binding protein| KFABP| Klbp| mal1| MDA_GLEAN10011553| N301_02698| N302_14428| N305_04328| N326_07385| N331_00655| PAFABP| PA-FABP| PAL_GLEAN10019396| PANDA_004888| psoriasis-associated fatty acid-binding protein homolog| putative fatty acid-binding protein 5-like protein 3| putative fatty acid binding protein 5 variant 1| TREES_T100009530| uncharacterized protein LOC16592| UY3_00463| fabp5

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