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  3. FABP4

FABP4 (Fatty acid binding protein 4)

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Summary of FABP4

This gene encodes a protein that binds to fatty acids in fat cells. It plays a role in fatty acid binding, uptake, transport, and metabolism (R).

Blood levels of FABP4 is linked to severity and treatment of obstructive sleep apnea, as well as the metabolic changes as a result of the apnea (R).

0 users want this gene increased, 0 users want it decreased

The Function of FABP4

Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.

Protein names

Recommended name:

Fatty acid-binding protein, adipocyte

Short name:

ALBP

Alternative name(s):

Adipocyte lipid-binding protein
Adipocyte-type fatty acid-binding protein
A-FABP
AFABP
Fatty acid-binding protein 4

FABP4 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS1054135 (FABP4) ??

Top Gene-Substance Interactions

FABP4 Interacts with These Diseases

Disease Score

Substances That Increase FABP4

Substances Interaction Organism Category

Substances That Decrease FABP4

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • PPAR-gamma2
  • PPAR-alpha
  • SREBP-1a
  • SREBP-1c
  • SREBP-1b

Gene Pathways:

  • Metabolism
  • PPAR signaling pathway
  • Mus musculus biological processes

Molecular Function:

  • Fatty Acid Binding
  • Transporter Activity

Biological Processes:

  • Brown Fat Cell Differentiation
  • Cellular Response To Lithium Ion
  • Cellular Response To Tumor Necrosis Factor
  • Cholesterol Homeostasis
  • Cytokine Production
  • Negative Regulation Of Protein Kinase Activity
  • Negative Regulation Of Transcription, Dna-Templated
  • Positive Regulation Of Inflammatory Response
  • Triglyceride Catabolic Process
  • White Fat Cell Differentiation

Drug Bank:

  • Oleic Acid
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| P15| FABP| 3T3-L1 lipid-binding protein| 422/aP2| adipocyte fatty acid binding protein| adipocyte fatty acid-binding protein 4| Adipocyte lipid-binding protein| adipocyte protein aP2| adipocyte-type fatty acid binding protein| adipocyte-type fatty acid-binding protein| adipose-type fatty acid-binding protein| AFABP| A-FABP| Albp| ALBP/Ap2| aP2| EGK_19076| epididymis secretory protein Li 104| FABP3| fatty acid-binding protein 4| fatty acid binding protein 4, adipocyte| Fatty acid-binding protein, adipocyte| fatty acid-binding protein, adipocyte-like protein| GW7_03359| H920_10386| HEL-S-104| Lbpl| myelin P2 protein homolog| P2 adipocyte protein| PAL_GLEAN10019398| PANDA_004885| protein 422| TREES_T100009520| fabp4

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