Summary of FABP2
The FABP2 gene encodes a protein called fatty acid binding protein 2 [R].
This protein may help with the body’s energy balance. It transports long-chain fatty acids and helps produce triglyceride-rich lipoproteins. It also senses and adjusts how many fat molecules are available for energy production [R].
Variants in the FABP2 gene have been associated with:
- High blood pressure [R]
- Metabolic syndrome [R]
- Type 2 diabetes [R]
- Glaucoma [R]
- Coronary artery disease [R]
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Protein names
Recommended name:
Fatty acid-binding protein, intestinalShort name:
I-FABPAlternative name(s):
Fatty acid-binding protein 2Intestinal-type fatty acid-binding protein
- RS10028773 (FABP2) ??
- RS1799883 (FABP2) ??
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Top Gene-Substance Interactions
FABP2 Interacts with These Diseases
| Disease | Score |
Substances That Increase FABP2
| Substances | Interaction | Organism | Category |
Substances That Decrease FABP2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.
Gene Pathways:
Induction:
By EGF.