The Function of ETV1
Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
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Protein names
Recommended name:
ETS translocation variant 1Alternative name(s):
Ets-related protein 81- RS7788657 (ETV1) ??
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Top Gene-Substance Interactions
ETV1 Interacts with These Diseases
| Disease | Score |
Substances That Increase ETV1
| Substances | Interaction | Organism | Category |
Substances That Decrease ETV1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
Molecular Function:
- Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Dna Binding
- Transcriptional Activator Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding
- Transcription Factor Activity, Sequence-Specific Dna Binding
Biological Processes:
- Axon Guidance
- Mechanosensory Behavior
- Muscle Organ Development
- Peripheral Nervous System Neuron Development
- Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
- Transcription From Rna Polymerase Ii Promoter