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  2. Genes
  3. ETS2

ETS2 (ETS proto-oncogene 2, transcription factor)

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The Function of ETS2

Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.

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Protein names

Recommended name:

Protein C-ets-2

ETS2 SNPs

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  1. RS1209950 (ETS2) ??

Top Gene-Substance Interactions

ETS2 Interacts with These Diseases

Disease Score

Substances That Increase ETS2

Substances Interaction Organism Category

Substances That Decrease ETS2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • GR
  • GR-alpha
  • GR-beta
  • CREB
  • deltaCREB
  • C/EBPbeta
  • GATA-1

Gene Pathways:

  • Cellular responses to stress
  • Dorso-ventral axis formation

Molecular Function:

  • Dna Binding
  • Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Dna Binding
  • Transcriptional Repressor Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding
  • Transcription Factor Activity, Sequence-Specific Dna Binding

Biological Processes:

  • Cell Differentiation
  • Ectodermal Cell Fate Commitment
  • Mesoderm Development
  • Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Positive Regulation Of Transcription, Dna-Templated
  • Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Primitive Streak Formation
  • Skeletal System Development
  • Transcription, Dna-Templated
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| Anapl_08197| AS27_04873| AS28_02949| avian erythroblastosis virus E26 (v-ets) oncogene homolog 2| avian leukemia oncogene 2| CB1_002182004| c-ets-2| D623_10002413| E26 avian leukemia oncogene 2, 3' domain| EGK_13242| erythroblastosis retrovirus oncogene homologue 2| erythroblastosis virus oncogene 2 protein homolog| ets-2| ets2-a| ets2-b| ets2it1| GW7_17153| H920_10521| I79_016729| M959_05778| N300_11106| N301_07336| N302_10705| N303_14936| N305_01736| N306_09232| N307_05600| N309_04801| N310_00472| N311_05207| N312_13207| N320_10694| N321_11306| N322_02974| N324_01689| N325_10845| N326_04311| N327_00294| N328_04729| N329_03727| N330_14328| N331_11584| N332_14810| N333_03805| N334_11198| N335_13155| N336_03088| N340_01660| N341_03861| oncogene ETS-2| PAL_GLEAN10008418| PANDA_018977| Protein C-ets-2| protein C-ets-2-like| protein C-ets-2-like protein| transcription factor Ets-2| TREES_T100007527| UY3_11368| v-ets avian erythroblastosis virus E26 oncogene homolog 2| v-ets avian erythroblastosis virus E26 oncogene-like protein 2| v-ets avian erythroblastosis virus E2 oncogene homolog 2| v-ets erythroblastosis virus E26 oncogene homolog 2| v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)| v-ets erythroblastosis virus E26 oncoprotein-like protein 2| Y1Q_017956| Y956_04422| ets2

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