The Function of ETS2
Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.
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Protein names
Recommended name:
Protein C-ets-2- RS1209950 (ETS2) ??
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Top Gene-Substance Interactions
ETS2 Interacts with These Diseases
| Disease | Score |
Substances That Increase ETS2
| Substances | Interaction | Organism | Category |
Substances That Decrease ETS2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
- Dna Binding
- Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Dna Binding
- Transcriptional Repressor Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding
- Transcription Factor Activity, Sequence-Specific Dna Binding
Biological Processes:
- Cell Differentiation
- Ectodermal Cell Fate Commitment
- Mesoderm Development
- Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
- Positive Regulation Of Transcription, Dna-Templated
- Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
- Primitive Streak Formation
- Skeletal System Development
- Transcription, Dna-Templated