Summary of ESRRB
This gene encodes a protein but its exact functions are unknown (R).
The Function of ESRRB
Nuclear receptor, may regulate ESR1 transcriptional activity. Induces the expression of PERM1 in the skeletal muscle.
Protein names
Recommended name:
Steroid hormone receptor ERR2Alternative name(s):
ERR beta-2Estrogen receptor-like 2
Estrogen-related receptor beta
ERR-beta
Nuclear receptor subfamily 3 group B member 2
- RS12893597 (ESRRB) ??
- RS2360997 (ESRRB) ??
- RS7156960 (ESRRB) ??
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Top Gene-Substance Interactions
Substances That Increase ESRRB
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Substances That Decrease ESRRB
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Advanced Summary
Covered on Genetics Home Reference: nonsyndromic hearing lossFrom NCBI Gene: Deafness, autosomal recessive 35From UniProt: Deafness, autosomal recessive, 35 (DFNB35): A form of non-syndromic deafness characterized by non-progressive, prelingual hearing loss. [MIM:608565]
From NCBI Gene: This gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development. [provided by RefSeq, Jul 2008] From UniProt: Nuclear receptor, may regulate ESR1 transcriptional activity. Induces the expression of PERM1 in the skeletal muscle.
Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
- Rna Polymerase Ii Distal Enhancer Sequence-Specific Dna Binding
- Rna Polymerase Ii Transcription Factor Activity, Ligand-Activated Sequence-Specific Dna Binding
- Sequence-Specific Dna Binding
- Steroid Binding
- Steroid Hormone Receptor Activity
- Transcription Coactivator Activity
- Transcription Factor Binding
- Zinc Ion Binding
Biological Processes:
- Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
- Regulation Of Transcription, Dna-Templated
- Transcription Initiation From Rna Polymerase Ii Promoter