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  3. EPB41L3

EPB41L3 (Erythrocyte membrane protein band 4.1 like 3)

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The Function of EPB41L3

Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N-methyltransferases, including PRMT3 and PRMT5.

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Protein names

Recommended name:

Band 4.1-like protein 3

Short name:

4.1B

Alternative name(s):

Differentially expressed in adenocarcinoma of the lung protein 1
DAL-1

EPB41L3 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS11664536 (EPB41L3) ??
  2. RS1539809 (EPB41L3) ??

Top Gene-Substance Interactions

Substances That Increase EPB41L3

Substances Interaction Organism Category

Substances That Decrease EPB41L3

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • GR
  • GR-alpha
  • GR-beta
  • p53
  • Max
  • IRF-1

Tissue specificity:

Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung.

Gene Pathways:

  • Tight junction

Molecular Function:

  • Structural Constituent Of Cytoskeleton

Biological Processes:

  • Actomyosin Structure Organization
  • Apoptotic Process
  • Cortical Actin Cytoskeleton Organization
  • Cortical Cytoskeleton Organization
  • Cytoskeletal Anchoring At Plasma Membrane
  • Myelin Maintenance
  • Neuron Projection Morphogenesis
  • Paranodal Junction Assembly
  • Protein Localization To Juxtaparanode Region Of Axon
  • Protein Localization To Paranode Region Of Axon
  • Protein Localization To Plasma Membrane
  • Regulation Of Cell Growth
  • Regulation Of Cell Shape
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| erythrocyte membrane protein band 4.1-like 3| 130kDa Protein 4.1B MEF cell isoform| 4.1B| 60kDa 4.1B MEF cell isoform| A306_01420| Anapl_06632| AS27_05816| Band 4.1-like 3| Band 4.1-like protein 3| CB1_000932005| D623_10019908| Dal1| DAL-1| DAL1P| differentially expressed in adenocarcinoma of the lung protein 1| EPB4.1L3| erythrocyte protein band 4.1 like 3| erythrocyte protein band 4.1-like 3| I79_014068| Kiaa0987| M91_08468| M959_00986| MDA_GLEAN10025277| mDAL-1| N300_05323| N301_04848| N303_01583| N305_03481| N306_04855| N307_14909| N308_00757| N311_11138| N312_06699| N325_11516| N330_14077| N331_02628| N332_10228| N333_09406| N340_03224| NBL3| PAL_GLEAN10023203| PANDA_014316| UY3_10852| Y1Q_029385| Z169_02888| epb41l3

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