The Function of EPB41L3
Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N-methyltransferases, including PRMT3 and PRMT5.
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Protein names
Recommended name:
Band 4.1-like protein 3Short name:
4.1BAlternative name(s):
Differentially expressed in adenocarcinoma of the lung protein 1DAL-1
- RS11664536 (EPB41L3) ??
- RS1539809 (EPB41L3) ??
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Top Gene-Substance Interactions
Substances That Increase EPB41L3
| Substances | Interaction | Organism | Category |
Substances That Decrease EPB41L3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung.
Gene Pathways:
Molecular Function:
Biological Processes:
- Actomyosin Structure Organization
- Apoptotic Process
- Cortical Actin Cytoskeleton Organization
- Cortical Cytoskeleton Organization
- Cytoskeletal Anchoring At Plasma Membrane
- Myelin Maintenance
- Neuron Projection Morphogenesis
- Paranodal Junction Assembly
- Protein Localization To Juxtaparanode Region Of Axon
- Protein Localization To Paranode Region Of Axon
- Protein Localization To Plasma Membrane
- Regulation Of Cell Growth
- Regulation Of Cell Shape